January 4, 2013 Interferon-free therapy for hepatitis C may become a reality

Interferon-free therapy for hepatitis C may become a reality

January 4, 2013
Medical News Today

A new exploratory agent has been tested in the treatment of the hepatitis C virus infection (HCV), allowing patients to avoid the current interferon treatment that comes with harsh side effects.

A clinical trial published in the New England Journal of Medicine has defined sofosbuvir, an oral nucleotide inhibitor of HCV polymerase, as successful in the treatment of HCV infection.

The standard treatment for the HCV infection is interferon, given by injection under the fat. Troublesome side effects are also found with interferon, including:
  • flu-like symtoms
  • fatigue
  • decrease in white blood count
  • depression
  • irritability
  • sleep disruptions
  • anxiety

The creation of orally administered medications have helped move forward the possibility of getting rid of interferon treatment and avoiding its harmful side effects and tedious application.

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